SIBO Full Protocol
Small intestinal bacterial overgrowth is common, misunderstood, and — most importantly — addressable.
View Microbiome Balance FormulaWhy this works
SIBO has two jobs, not one: clear the overgrowth, then fix the motility problem that let it happen in the first place. Every ingredient here is doing one of those two jobs — not filler, not a proprietary blend guessing game.
Split AM / PM, 2 packs a day, 30-day supply. Made in the USA in cGMP and NSF-certified facilities. Non-GMO, vegan.
Why daily packs, not bottles
Getting all 8 of the ingredients above right means managing 8 separate bottles — 8 different doses, 8 different timings, hoping you don't run out of one before the others. We pack them into single AM and PM packs instead: the exact dose, already sorted, already timed. Tear one open and go.
8 bottles worth of dosing — 1 pack
What SIBO actually is
Your gut is supposed to keep most of its bacteria in the large intestine. SIBO happens when bacteria migrate into the small intestine, where they don't belong. When you eat — especially healthy, fibrous foods — that bacteria ferments it early and produces gas. The small intestine can't expand the way the large intestine can, so that gas has nowhere to go. That's the bloated, "bomb went off" feeling so many people describe.
Symptoms to look for
- Bloating 30-60 minutes after meals
- Healthy foods (vegetables, fiber) making bloating worse, not better
- Diarrhea or constipation - depending on the gas type driving it
Hydrogen-dominant SIBO tends to run with diarrhea. Methane-dominant tends to run with constipation. That's why two people with SIBO can have opposite bathroom symptoms.
The two root causes
Almost everything traces back to two things: slowed gut motility and low stomach acid. Both let bacteria travel and build up where they shouldn't.
What slows motility: chronic stress, low daily movement, GLP-1 medications (Ozempic, etc.), constant snacking.
What lowers stomach acid: PPIs, chronic stress, H. pylori infection, aging.
How to know for sure
A SIBO breath test - through your doctor, or an at-home kit - is the way to confirm it rather than guess. That said, if the symptoms above line up with your experience (especially bloating tied to a GLP-1, a stressful stretch, or healthy food suddenly not agreeing with you), that pattern alone is usually enough to act on.
Phase 1
Calm it down with diet
A low-FODMAP diet cuts off the fermentable food the bacteria are feeding on - most people notice less bloating almost immediately. Pair it with spacing out meals instead of snacking, which helps restart gut motility. This phase isn't forever - just the first ~week, to calm things down before the next phase.
What "low-FODMAP" actually means
FODMAPs are fermentable carbs — the exact fuel bacteria use to produce the gas behind SIBO bloating. Cutting them back for this first week starves the overgrowth while everything else gets to work.
This is a short reset, not a forever diet — most people only need this restriction for about a week before moving into Phase 2.
Phase 2
Address the overgrowth
This is where the berberine, NAC, and ginger from above go to work together. Expect some initial discomfort as this phase works - that's normal, not a red flag. This phase typically runs 1-3 months.
Phase 3
Reseed the gut
Once the overgrowth is under control, it's time to repopulate with the probiotics your gut actually needs. Dr. William Davis (Super Gut) recommends L. reuteri specifically here - one of the few strains that colonizes the upper GI tract and helps prevent the overgrowth from coming back. Alongside this: manage stress and stay consistently active, since both directly support motility and stomach acid.
How to make your own L. reuteri yogurt
The exact fermentation method for Phase 3, step by step.
What this actually costs
Rifaximin alone frequently runs well over $1,000 without insurance. Buying berberine, NAC, a probiotic, ginger, and a gut-lining formula separately — at the doses this protocol uses — typically costs more than that per month, before a practitioner visit.
This is $154 for the full 30 days — all six components, already dosed and timed.
The 30-Day Reset Guarantee
Run the full 30 days. If you don't feel a difference, we'll refund your first protocol — nothing to send back. One per household, first protocol only.
Formulated with Dr. Andrew Brandeis
Try it for a month. Subscribe to lock in your discount - cancel anytime once your symptoms have cleared, which typically takes 1-3 months.
This content is for informational purposes only and is not medical advice. These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure, or prevent any disease. Talk to your doctor before starting any new protocol.