SIBO Full Protocol



Small intestinal bacterial overgrowth is common, misunderstood, and — most importantly — addressable.

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Why this works

SIBO has two jobs, not one: clear the overgrowth, then fix the motility problem that let it happen in the first place. Every ingredient here is doing one of those two jobs — not filler, not a proprietary blend guessing game.

Berberine 500mg, twice daily
Shifts bacterial balance toward the strains you want, while targeting the overgrowth directly 180-patient RCT, Frontiers in Pharmacology 2023
NAC 600mg
Breaks down the biofilm bacteria hide behind, so berberine works harder BMC Microbiology, 2010
Organic Ginger Root 1,000mg
A real prokinetic — restarts the gut's cleaning wave, the step most competing formulas skip Randomized double-blind trial, Eur J Gastroenterol Hepatol 2008
L-Glutamine 750mg
The primary fuel source for the cells lining your small intestine during repair Mechanistic review, PMC
Quercetin + Zinc 500mg / 25mg (227% DV)
Calms the histamine response an irritated gut kicks up, and supports the gut barrier directly Quercetin: human mast cell study, PLOS ONE
Soothing Fiber Complex Aloe, marshmallow root, slippery elm
Forms a soothing layer over irritated tissue while everything else works
8-Strain Probiotic + FOS 10B CFU
Repopulates the colon, so bacteria have a reason to stay downstream Meta-analysis, J Clin Gastroenterol 2017

Split AM / PM, 2 packs a day, 30-day supply. Made in the USA in cGMP and NSF-certified facilities. Non-GMO, vegan.



Why daily packs, not bottles

Getting all 8 of the ingredients above right means managing 8 separate bottles — 8 different doses, 8 different timings, hoping you don't run out of one before the others. We pack them into single AM and PM packs instead: the exact dose, already sorted, already timed. Tear one open and go.

1 PACK

8 bottles worth of dosing — 1 pack

Herbal Cleanse daily packs



What SIBO actually is

Your gut is supposed to keep most of its bacteria in the large intestine. SIBO happens when bacteria migrate into the small intestine, where they don't belong. When you eat — especially healthy, fibrous foods — that bacteria ferments it early and produces gas. The small intestine can't expand the way the large intestine can, so that gas has nowhere to go. That's the bloated, "bomb went off" feeling so many people describe.



Symptoms to look for

  • Bloating 30-60 minutes after meals
  • Healthy foods (vegetables, fiber) making bloating worse, not better
  • Diarrhea or constipation - depending on the gas type driving it

Hydrogen-dominant SIBO tends to run with diarrhea. Methane-dominant tends to run with constipation. That's why two people with SIBO can have opposite bathroom symptoms.



The two root causes

Almost everything traces back to two things: slowed gut motility and low stomach acid. Both let bacteria travel and build up where they shouldn't.

What slows motility: chronic stress, low daily movement, GLP-1 medications (Ozempic, etc.), constant snacking.

What lowers stomach acid: PPIs, chronic stress, H. pylori infection, aging.



How to know for sure

A SIBO breath test - through your doctor, or an at-home kit - is the way to confirm it rather than guess. That said, if the symptoms above line up with your experience (especially bloating tied to a GLP-1, a stressful stretch, or healthy food suddenly not agreeing with you), that pattern alone is usually enough to act on.



Phase 1

Calm it down with diet

A low-FODMAP diet cuts off the fermentable food the bacteria are feeding on - most people notice less bloating almost immediately. Pair it with spacing out meals instead of snacking, which helps restart gut motility. This phase isn't forever - just the first ~week, to calm things down before the next phase.



What "low-FODMAP" actually means

FODMAPs are fermentable carbs — the exact fuel bacteria use to produce the gas behind SIBO bloating. Cutting them back for this first week starves the overgrowth while everything else gets to work.

Foods to enjoy

Protein

Chicken, beef, fish, eggs, firm tofu

Vegetables

Carrots, cucumber, spinach, zucchini, bell peppers, tomatoes, potatoes

Fruit

Strawberries, blueberries, oranges, grapes, kiwi, pineapple

Grains

Rice, oats, quinoa, gluten-free bread

Dairy & alternatives

Lactose-free milk, hard cheeses, almond milk

Foods to limit

Vegetables

Onion, garlic, mushrooms, cauliflower, asparagus

Fruit

Apples, pears, mango, watermelon, cherries

Grains

Wheat bread, rye, barley

Dairy

Milk, soft cheese, regular yogurt

Legumes

Beans, lentils, chickpeas

Sweeteners

Honey, high-fructose corn syrup, sugar alcohols (sorbitol, xylitol)

This is a short reset, not a forever diet — most people only need this restriction for about a week before moving into Phase 2.



Phase 2

Address the overgrowth

This is where the berberine, NAC, and ginger from above go to work together. Expect some initial discomfort as this phase works - that's normal, not a red flag. This phase typically runs 1-3 months.



Phase 3

Reseed the gut

Once the overgrowth is under control, it's time to repopulate with the probiotics your gut actually needs. Dr. William Davis (Super Gut) recommends L. reuteri specifically here - one of the few strains that colonizes the upper GI tract and helps prevent the overgrowth from coming back. Alongside this: manage stress and stay consistently active, since both directly support motility and stomach acid.



How to make your own L. reuteri yogurt

The exact fermentation method for Phase 3, step by step.



What this actually costs

Rifaximin alone frequently runs well over $1,000 without insurance. Buying berberine, NAC, a probiotic, ginger, and a gut-lining formula separately — at the doses this protocol uses — typically costs more than that per month, before a practitioner visit.

This is $154 for the full 30 days — all six components, already dosed and timed.



The 30-Day Reset Guarantee

Run the full 30 days. If you don't feel a difference, we'll refund your first protocol — nothing to send back. One per household, first protocol only.



Formulated with Dr. Andrew Brandeis



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This content is for informational purposes only and is not medical advice. These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure, or prevent any disease. Talk to your doctor before starting any new protocol.

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